Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1375841 | 0.80 | HRH3 (0.68) | HRH3KCNH2 | |
| SCHEMBL12148525 | 0.73 | HRH3 (0.53) | HRH3KCNH2ADRA1A | |
| SCHEMBL1373911 | 0.71 | HRH3 (0.69) | HRH3KCNH2 | |
| SCHEMBL1372726 | 0.69 | HRH3 (0.65) | HRH3KCNH2 | |
| SCHEMBL1372844 | 0.68 | HRH3 (0.64) | HRH3KCNH2 | |
| SCHEMBL1375901 | 0.67 | HRH3 (0.70) | HRH3KCNH2 | |
| SCHEMBL1375384 | 0.66 | HRH3 (0.58) | HRH3KCNH2 | |
| SCHEMBL1373356 | 0.66 | HRH3 (0.59) | HRH3KCNH2 | |
| SCHEMBL8225123 | 0.65 | MEN1 (0.49) | HRH3KCNH2 | |
| SCHEMBL15784148 | 0.65 | ATR (0.42) | HRH3KCNH2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069312-B1 | PYRIDIZINONE DERIVATIVES | CEPHALON INC (US) | 2012-11-07 | — | — | EP | disclosed |