SCHEMBL136424

SCHEMBL136424

O=CC#Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.55
NPC1 O15118 2/20 0.43
MTOR P42345 1/20 0.43
RAB9A P51151 1/20 0.43
MAPT P10636 2/20 0.42
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
THPO P40225 1/20 0.41
FFAR1 O14842 2/20 0.41
CA12 O43570 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
CA1 P00915 1/20 0.40
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
GRM5 P41594 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ALDH1A1 P00352 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19929750 0.83 APP (0.48) APPNPC1MTORRAB9AMAPT
SCHEMBL9490159 0.81 APP (0.46) APPNPC1MTORRAB9AMAPT
SCHEMBL5507856 0.78 APP (0.61) APPNPC1MTORRAB9AMAPT
SCHEMBL9146168 0.78 APP (0.61) APPNPC1MTORRAB9AMAPT
SCHEMBL5507858 0.78 APP (0.61) APPNPC1MTORRAB9AMAPT
SCHEMBL15912585 0.77 APP (0.46) APPNPC1MTORRAB9AMAPT
Diphenylacetylene SCHEMBL30472716 0.76 APP (0.67) APPNPC1MTORRAB9AMAPT
SCHEMBL24975216 0.75 MAOB (0.57) RAB9AMAPTCYP1A2CYP2C19FFAR1
SCHEMBL728587 0.75 CA12 (0.45) NPC1MAPTFFAR1CA12CA2
SCHEMBL13620350 0.75 APP (0.59) APPNPC1MTORRAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 633 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118291822-A Processing method and application of rare earth 6 series aluminum alloy and profile 苏州创泰合金材料有限公司 2024-07-05 CN claimed
US-20230215723-A1 METHODS OF MANUFACTURING INTEGRATED CIRCUIT DEVICES USING CARBONYL COMPOUNDS ADEKA CORPORATION (JP) 2023-07-06 US claimed
CN-110437106-B Aryl amidine compound and synthetic method thereof 广东药科大学 2021-09-07 CN claimed
CN-112300157-B Novel pyrazolopyridine compound with anti-tumor activity and preparation method thereof 烟台大学 2021-08-20 CN claimed
CN-111689826-B Catalytic selective hydrogenation method 中国科学技术大学 2021-07-06 CN claimed
CN-107949596-B Semi-crystalline polyamide component with high glass transition temperature for composite materials, method for the production thereof and use thereof 阿科玛法国公司 2021-02-02 CN claimed
CN-112300157-A Novel pyrazolopyridine compound with anti-tumor activity and preparation method thereof 烟台大学 2021-02-02 CN claimed
CN-111689826-A Catalytic selective hydrogenation method 中国科学技术大学 2020-09-22 CN claimed
WO-2019232663-A1 AMINO-SUBSTITUTED INDOLIZINE COMPOUND HAVING ANTICANCER ACTIVITY AND DERIVATIVE THEREOF 广东药科大学 (CN) 2019-12-12 WO claimed
CN-106854159-B A kind of phenylacetylene carbonyl compound at unsaturated aromatic ester method 中国科学院大连化学物理研究所 2019-01-04 CN claimed
JP-2005524240-A 2005-08-11 JP claimed
US-6852474-B2 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE INC. (US) 2005-02-08 US claimed
EP-1502292-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION Brewer Science, Inc. (US) 2005-02-02 EP claimed
CN-1558898-A Antiviral agent ��Ұ����ҩ��ʽ���� 2004-12-29 CN claimed
EP-1422218-A1 ANTIVIRAL AGENT SHIONOGI & CO., LTD. (JP) 2004-05-26 EP claimed
US-20030224586-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-12-04 US claimed
WO-2003094213-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE, INC. (US) 2003-11-13 WO claimed
EP-0146373-B1 PROCESS FOR OXIDIZING ALDEHYDES TO CARBOXYLIC ACIDS Montedison S.p.A. (IT) 1986-11-05 EP claimed
US-4549025-A REACTING WITH CHLORITES MONTEDISON S.P.A. (IT) 1985-10-22 US claimed
EP-0099303-A2 Benzothiopyranopyridinones and their salts, their preparation and use as medicaments, and compositions containing them ROUSSEL-UCLAF (FR) 1984-01-25 EP claimed