Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.42 |
| ▸ | MAP3K8 | P41279 | 8/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.37 |
| ▸ | SRC | P12931 | 4/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2308992 | 0.87 | ABL1 (0.43) | CSNK2A2MAP3K8MAPK13SRCMAPK12 | |
| SCHEMBL3309645 | 0.80 | CSNK2A2 (0.47) | CSNK2A2FGFR4 | |
| SCHEMBL12013318 | 0.80 | CSNK2A2 (0.46) | CSNK2A2 | |
| SCHEMBL3312928 | 0.79 | CSNK2A2 (0.49) | CSNK2A2 | |
| SCHEMBL3313360 | 0.79 | CSNK2A1 (0.45) | CSNK2A2MAP3K8FGFR4MAPK13SRC | |
| SCHEMBL3311734 | 0.79 | CSNK2A2 (0.48) | CSNK2A2 | |
| SCHEMBL3311584 | 0.77 | CSNK2A2 (0.41) | CSNK2A2MAP3K8MAPK13SRCMAPK12 | |
| SCHEMBL3313759 | 0.76 | TYK2 (0.49) | CSNK2A2MAP3K8MAPK13SRCMAPK12 | |
| SCHEMBL2358177 | 0.76 | CSNK2A2 (0.62) | CSNK2A2 | |
| SCHEMBL13421562 | 0.75 | ABL1 (0.45) | CSNK2A2ABL1BCRIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283241-A1 | IMIDAZOPYRIDAZINECARBONITRILES USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283241-A1 | IMIDAZOPYRIDAZINECARBONITRILES USEFUL AS KINASE INHIBITORS | MAP3K5, MAP3K15, MAP4K2 | CSNK2A2 135/4885MAP3K8 9/4885FGFR4 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.