Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15605706 | 0.89 | USP2 (0.46) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL6481562 | 0.77 | KDM4E (0.41) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL80815 | 0.74 | USP2 (0.36) | USP2ALDH1A1LMNATSHR | |
| SCHEMBL150831 | 0.74 | USP2 (0.36) | USP2ALDH1A1LMNATSHR | |
| SCHEMBL6485137 | 0.74 | KDM4E (0.43) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL28193387 | 0.74 | USP2 (0.36) | USP2ALDH1A1LMNATSHR | |
| SCHEMBL6570483 | 0.74 | USP2 (0.36) | USP2ALDH1A1LMNATSHR | |
| SCHEMBL613567 | 0.74 | USP2 (0.36) | USP2ALDH1A1LMNATSHR | |
| SCHEMBL15103122 | 0.74 | USP2 (0.36) | USP2ALDH1A1LMNATSHR | |
| SCHEMBL17376011 | 0.74 | USP2 (0.36) | USP2ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601843-B2 | 4-(2-furoyl)aminopiperidine compound useful as therapeutic agent for itching | KYORIN PHARMACEUTICAL CO., LTD (JP) | 2009-10-13 | — | — | US | disclosed |