SCHEMBL13645528

SCHEMBL13645528

CN(C)C=CC1=[N+](CCCC[N+]2=C(C=CN(C)C)C(C)(C)c3ccc(Cl)cc32)c2cc(Cl)ccc2C1(C)C

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 3/20 0.39
MAPT P10636 3/20 0.38
APP P05067 1/20 0.38
ALDH1A1 P00352 2/20 0.31
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PTPN1 P18031 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
THRB P10828 1/20 0.30
HTT P42858 1/20 0.30
RECQL P46063 1/20 0.30
KMT2A Q03164 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13645521 0.93 PRMT1 (0.39) PRMT1MAPTAPPPTPN1
SCHEMBL13645395 0.84 APP (0.41) PRMT1MAPTAPP
SCHEMBL13672225 0.78 MAPT (0.66) PRMT1MAPTAPPALDH1A1NPC1
SCHEMBL13672213 0.77 MAPT (0.64) PRMT1MAPTAPPALDH1A1NPC1
SCHEMBL13645482 0.75 MAPT (0.51) PRMT1MAPTAPPALDH1A1NPC1
SCHEMBL13645519 0.75 MEN1 (0.40) PRMT1MAPTMEN1LMNATHRB
SCHEMBL13645556 0.72 APP (0.38) PRMT1MAPTAPP
SCHEMBL16316020 0.71 MAPT (0.44) PRMT1MAPTAPPNPC1POLB
SCHEMBL9910787 0.70 MAPT (0.46) PRMT1MAPTAPPNPC1POLB
SCHEMBL9910802 0.69 MAPT (0.45) PRMT1MAPTAPPALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7598360-B2 High density recording media with modified recording layers of the invention provides better photoelectrical performance; high recording sensitivity and high carrier-to-noise ratio; blue-laser high density recording media INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2009-10-06 US disclosed
US-20070009825-A1 Bisstyryl compound and high density recording media utilizing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2007-01-11 US disclosed