Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.56 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13645589 | 0.91 | TLR7 (0.52) | TLR7TLR8STING1 | |
| SCHEMBL3863711 | 0.90 | TLR7 (0.53) | TLR7TLR8NUDT1 | |
| SCHEMBL483393 | 0.89 | TLR7 (0.50) | TLR7TLR8NUDT1 | |
| SCHEMBL30345892 | 0.89 | TLR7 (0.50) | TLR7TLR8NUDT1 | |
| SCHEMBL483008 | 0.89 | TLR7 (0.50) | TLR7TLR8NUDT1 | |
| SCHEMBL31006045 | 0.89 | TLR7 (0.50) | TLR7TLR8NUDT1 | |
| SCHEMBL6105201 | 0.88 | TLR7 (0.49) | TLR7TLR8NUDT1 | |
| SCHEMBL6105492 | 0.87 | TLR7 (0.48) | TLR7TLR8NUDT1 | |
| SCHEMBL6104268 | 0.85 | TLR7 (0.57) | TLR7TLR8NUDT1 | |
| SCHEMBL31337596 | 0.85 | TLR7 (0.59) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598382-B2 | Aryl substituted imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7598382-B2 | Aryl substituted imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-10-06 | — | — | US | disclosed |