Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3865532 | 0.99 | TLR7 (0.52) | TLR7TLR8NUDT1DHFR | |
| SCHEMBL3867682 | 0.91 | TLR7 (0.61) | TLR7TLR8NUDT1 | |
| SCHEMBL13645622 | 0.91 | TLR7 (0.45) | TLR7TLR8DHFR | |
| Hydrochloric Acid SCHEMBL3861993 | 0.90 | TLR7 (0.60) | TLR7TLR8NUDT1 | |
| Hydrochloric Acid SCHEMBL3862202 | 0.90 | TLR7 (0.45) | TLR7TLR8DHFR | |
| SCHEMBL6246979 | 0.90 | TLR7 (0.51) | TLR7TLR8DHFR | |
| Hydrochloric Acid SCHEMBL3864091 | 0.89 | TLR7 (0.50) | TLR7TLR8DHFR | |
| SCHEMBL21315513 | 0.88 | TLR7 (0.50) | TLR7TLR8NUDT1DHFR | |
| SCHEMBL13645793 | 0.88 | TLR7 (0.47) | TLR7TLR8NUDT1DHFR | |
| SCHEMBL893197 | 0.87 | TLR7 (0.49) | TLR7TLR8NUDT1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598382-B2 | Aryl substituted imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7598382-B2 | Aryl substituted imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-10-06 | — | — | US | disclosed |