Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 16/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3871188 | 0.92 | TLR7 (0.49) | TLR7TLR8NUDT1 | |
| SCHEMBL3871193 | 0.92 | TLR7 (0.49) | TLR7TLR8NUDT1 | |
| SCHEMBL3862230 | 0.88 | TLR7 (0.50) | TLR7TLR8NUDT1 | |
| SCHEMBL13645812 | 0.87 | TLR7 (0.50) | TLR7TLR8NUDT1 | |
| SCHEMBL6105492 | 0.85 | TLR7 (0.48) | TLR7TLR8NUDT1 | |
| SCHEMBL3871201 | 0.83 | TLR7 (0.65) | TLR7TLR8NUDT1 | |
| SCHEMBL3871208 | 0.83 | TLR7 (0.65) | TLR7TLR8NUDT1 | |
| SCHEMBL1616868 | 0.82 | TLR8 (0.61) | TLR7TLR8NUDT1 | |
| SCHEMBL3867722 | 0.81 | TLR8 (0.49) | TLR7TLR8NUDT1 | |
| SCHEMBL3867728 | 0.81 | TLR8 (0.49) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598382-B2 | Aryl substituted imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7598382-B2 | Aryl substituted imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-10-06 | — | — | US | disclosed |