Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.31 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374837 | 1.00 | MEN1 (0.33) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL12375377 | 1.00 | MEN1 (0.33) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL12375378 | 0.91 | MEN1 (0.32) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL12375010 | 0.91 | MEN1 (0.32) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL12943362 | 0.83 | MEN1 (0.33) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL13777714 | 0.82 | MEN1 (0.36) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL14393325 | 0.81 | SARS1 (0.40) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL12374009 | 0.81 | SARS1 (0.40) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL10146720 | 0.78 | MEN1 (0.33) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL13777765 | 0.78 | MEN1 (0.33) | MEN1ALDH1A1LMNACYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605143-B2 | 2-propynyl adenosine analogs with modified 5′-ribose groups having A2A agonist activity | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2009-10-20 | — | — | US | disclosed |