Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.74 |
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.53 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3862484 | 0.87 | TLR7 (0.64) | TLR7TLR8 | |
| SCHEMBL1486429 | 0.86 | TLR7 (0.79) | TLR7TLR8NUDT1 | |
| SCHEMBL3865770 | 0.85 | TLR7 (0.78) | TLR7TLR8NUDT1 | |
| SCHEMBL22558521 | 0.85 | TLR7 (1.00) | TLR7TLR8NUDT1 | |
| SCHEMBL4535615 | 0.85 | TLR7 (0.75) | TLR7TLR8NUDT1 | |
| SCHEMBL3861903 | 0.85 | TLR7 (0.66) | TLR7TLR8NUDT1 | |
| SCHEMBL3871208 | 0.84 | TLR7 (0.65) | TLR7TLR8NUDT1 | |
| SCHEMBL3871201 | 0.84 | TLR7 (0.65) | TLR7TLR8NUDT1 | |
| SCHEMBL13645717 | 0.84 | TLR8 (0.53) | TLR7TLR8NUDT1 | |
| SCHEMBL3867963 | 0.82 | TLR7 (0.74) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598382-B2 | Aryl substituted imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7598382-B2 | Aryl substituted imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-10-06 | — | — | US | disclosed |