Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835729 | 0.93 | HDAC1 (0.55) | HDAC1HDAC6HDAC3HDAC2NCOR2 | |
| SCHEMBL2478629 | 0.93 | HDAC1 (0.58) | HDAC1HDAC6HDAC3HDAC2NCOR2 | |
| SCHEMBL2475158 | 0.93 | HDAC1 (0.57) | HDAC1HDAC6HDAC3HDAC2NCOR2 | |
| SCHEMBL2506885 | 0.93 | HDAC1 (0.55) | HDAC1HDAC6HDAC3HDAC2NCOR2 | |
| SCHEMBL2496863 | 0.92 | HDAC1 (0.57) | HDAC1HDAC6HDAC3HDAC2NCOR2 | |
| SCHEMBL2474043 | 0.92 | HDAC1 (0.56) | HDAC1HDAC6HDAC3HDAC2NCOR2 | |
| SCHEMBL2474812 | 0.92 | HDAC1 (0.58) | HDAC1HDAC6HDAC3HDAC2NCOR2 | |
| SCHEMBL4389887 | 0.92 | HDAC1 (0.54) | HDAC1HDAC6HDAC3HDAC2NCOR2 | |
| SCHEMBL2474131 | 0.90 | HDAC1 (0.56) | HDAC1HDAC6HDAC3HDAC2NCOR2 | |
| SCHEMBL3837782 | 0.90 | HDAC1 (0.52) | HDAC1HDAC6HDAC3HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-A1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-10-07 | — | — | EP | disclosed |