Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026934 | 1.00 | ADRB3 (0.41) | ADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL10254639 | 1.00 | ADRB3 (0.41) | ADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL12315733 | 1.00 | ADRB3 (0.41) | ADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL8243274 | 0.92 | ADRB3 (0.44) | ADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL13059010 | 0.90 | ADRB3 (0.43) | ADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL13630595 | 0.90 | ADRB3 (0.40) | ADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL8037005 | 0.90 | ADRB3 (0.40) | ADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL13646429 | 0.90 | ADRB3 (0.40) | ADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL2133849 | 0.90 | ADRB3 (0.40) | ADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL3793643 | 0.90 | ADRB3 (0.40) | ADRB3ADRA2BADRA2CCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601709-B2 | Macrocyclic hepatitis C serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2009-10-13 | — | — | US | disclosed |