SCHEMBL13648705

SCHEMBL13648705

CCCNC(=O)c1cccc(Nc2nc3cc(/C(N)=N/N=N)ccc3c3sccc23)c1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13648719 0.92 CSNK2A1 (0.65) CSNK2A1
SCHEMBL13648707 0.92 CSNK2A1 (0.77) CSNK2A1
SCHEMBL13687966 0.90 CSNK2A1 (0.75) CSNK2A1
SCHEMBL13648708 0.89 CSNK2A1 (0.60) CSNK2A1
SCHEMBL13648710 0.88 CSNK2A1 (0.59) CSNK2A1
SCHEMBL10132689 0.87 CSNK2A1 (1.00) CSNK2A1
SCHEMBL13649099 0.87 CSNK2A1 (0.69) CSNK2A1
SCHEMBL13648714 0.86 CSNK2A1 (0.77) CSNK2A1
SCHEMBL13648716 0.86 CSNK2A1 (0.58) CSNK2A1
SCHEMBL13648712 0.85 CSNK2A1 (0.62) CSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090264423-A2 SERINE-THREONINE PROTEIN KINASE AND PARP MODULATORS CYLENE PHARMACEUTICALS, INC. (US) 2009-10-22 US disclosed
US-20090264423-A2 SERINE-THREONINE PROTEIN KINASE AND PARP MODULATORS CYLENE PHARMACEUTICALS, INC. (US) 2009-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090264423-A2 SERINE-THREONINE PROTEIN KINASE AND PARP MODULATORS PACSIN2, TNKS, PARP1 CSNK2A1 24/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.