Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 12/20 | 0.43 |
| ▸ | PNP | P00491 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243638 | 0.81 | HPRT1 (0.49) | HPRT1PNPALDH1A1LMNAALB | |
| SCHEMBL21625880 | 0.80 | ADORA2A (0.56) | HPRT1PNPLMNA | |
| SCHEMBL21417461 | 0.80 | HPRT1 (0.50) | HPRT1PNPALDH1A1LMNA | |
| SCHEMBL21385661 | 0.78 | HPRT1 (0.55) | HPRT1PNPALDH1A1LMNAALB | |
| SCHEMBL7812368 | 0.76 | HPRT1 (0.47) | HPRT1PNPALDH1A1LMNAALB | |
| SCHEMBL784333 | 0.76 | ADORA2A (0.51) | HPRT1PNPALDH1A1LMNA | |
| SCHEMBL11243652 | 0.76 | HPRT1 (0.49) | HPRT1PNPALDH1A1LMNAALB | |
| SCHEMBL23619296 | 0.75 | HPRT1 (0.46) | HPRT1PNPLMNA | |
| SCHEMBL21127932 | 0.74 | HPRT1 (0.47) | HPRT1PNPALDH1A1LMNA | |
| SCHEMBL7396872 | 0.73 | HPRT1 (0.46) | HPRT1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598246-B2 | Bisphosphonate conjugates and methods of making and using the same | MBC PHARMA, INC. (US) | 2009-10-06 | — | — | US | disclosed |