Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.69 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29440247 | 0.99 | CYP1A1 (0.69) | MEN1KMT2AALDH1A1MAPK1CYP1A1 | |
| Bromide SCHEMBL22749628 | 0.99 | CYP1A1 (0.69) | MEN1KMT2AALDH1A1MAPK1CYP1A1 | |
| Bromide SCHEMBL22749627 | 0.98 | MEN1 (0.66) | MEN1KMT2AALDH1A1MAPK1CYP1A1 | |
| SCHEMBL22761628 | 0.85 | MEN1 (0.64) | MEN1KMT2AALDH1A1MAPK1CYP1A1 | |
| Bromide SCHEMBL22749448 | 0.84 | CYP1A1 (0.65) | MEN1KMT2AALDH1A1MAPK1CYP1A1 | |
| Bromide SCHEMBL29440246 | 0.84 | CYP1A1 (0.65) | MEN1KMT2AALDH1A1MAPK1CYP1A1 | |
| SCHEMBL13650867 | 0.83 | KMT2A (0.69) | MEN1KMT2AALDH1A1MAPK1CYP1A1 | |
| Bromide SCHEMBL22749447 | 0.83 | MEN1 (0.61) | MEN1KMT2AALDH1A1MAPK1CYP1A1 | |
| SCHEMBL13650924 | 0.81 | MAPT (0.77) | MEN1KMT2AALDH1A1MAPK1CYP1A1 | |
| SCHEMBL158627 | 0.81 | KMT2A (1.00) | MEN1KMT2AALDH1A1MAPK1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247336-A1 | PIFITHRIN ANALOGUES AND METHODS OF TREATING RETT SYNDROME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-12-10 | — | — | WO | disclosed |
| US-7601846-B2 | Compounds having activity as inhibitors of apoptosis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-10-13 | — | — | US | disclosed |