SCHEMBL1365239

SCHEMBL1365239

c1cc(-c2cccc3ocnc23)c2ncoc2c1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.39
DHODH Q02127 1/20 0.39
PIN1 Q13526 2/20 0.36
IDH1 O75874 1/20 0.32
EPHB4 P54760 1/20 0.32
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
KLKB1 P03952 1/20 0.31
XDH P47989 1/20 0.31
SLC22A12 Q96S37 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27527824 0.87 TOP2A (0.42) NR4A2DHODHPIN1XDHSLC22A12
SCHEMBL12637430 0.87 NPC1 (0.40) NR4A2DHODHPIN1KLKB1
SCHEMBL1884974 0.86 NR4A2 (0.43) NR4A2DHODHPIN1
SCHEMBL12637424 0.85 MAPT (0.45)
SCHEMBL12637425 0.82 NR4A2 (0.42) NR4A2DHODHPIN1KLKB1XDH
SCHEMBL7541667 0.82 NR4A2 (0.33) NR4A2DHODHIDH1HTR2AHTR2C
SCHEMBL28609509 0.82 NR4A2 (0.35) NR4A2DHODHPIN1IDH1KLKB1
SCHEMBL26267083 0.82 NAMPT (0.39) NR4A2DHODH
SCHEMBL12637427 0.82 NOTUM (0.47)
SCHEMBL11087318 0.82 NR4A2 (0.33) NR4A2DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11692090-B2 Dielectric cross-linked fluoropolymer DAIKIN AMERICA, INC. (US) 2023-07-04 US disclosed
US-11567051-B2 Nanoreactors as thermal history indicators WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-01-31 US disclosed
US-20210032453-A1 DIELECTRIC CROSS-LINKED FLUOROPOLYMER DAIKIN AMERICA, INC. (US) 2021-02-04 US disclosed
US-20200278335-A1 NANOREACTORS AS THERMAL HISTORY INDICATORS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2020-09-03 US disclosed
US-8067612-B2 Method for producing bisbenzoxazoles CLARIANT FINANCE (BVI) LIMITED (VG) 2011-11-29 US disclosed
US-20100076040-A1 Method For Producing Bisbenzoxazoles Clariant Finance Wickhams Cay (VG) 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076040-A1 Method For Producing Bisbenzoxazoles DDO, DAO, AADAC NR4A2 3953/4885DHODH 47/4885PIN1 953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.