Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 14/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13654033 | 0.92 | OPRL1 (0.32) | OPRL1BRD4HTR2AHTR2CSLC6A2 | |
| SCHEMBL12994355 | 0.91 | HTR2A (0.34) | OPRL1BRD4HTR2AHTR2C | |
| SCHEMBL12994442 | 0.90 | HTR2A (0.33) | OPRL1BRD4HTR2AHTR2C | |
| SCHEMBL12739701 | 0.89 | CYP2C9 (0.35) | OPRL1HTR2AHTR2C | |
| SCHEMBL12739694 | 0.87 | OPRL1 (0.34) | OPRL1HTR2AHTR2C | |
| SCHEMBL12823693 | 0.86 | OPRL1 (0.36) | OPRL1BRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13586604 | 0.86 | OPRL1 (0.36) | OPRL1BRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10302154 | 0.86 | OPRL1 (0.33) | OPRL1HTR2AHTR2C | |
| SCHEMBL12906891 | 0.85 | OPRL1 (0.32) | OPRL1HTR2AHTR2C | |
| SCHEMBL10302155 | 0.84 | S1PR1 (0.33) | OPRL1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009125668-A1 | TRICYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | チッソ株式会社 (JP) | 2009-10-15 | — | — | WO | disclosed |