Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989751 | 0.91 | PIK3CA (0.80) | PIK3CAPIK3CB | |
| SCHEMBL12555267 | 0.87 | PIK3CA (0.83) | PIK3CAPIK3CB | |
| SCHEMBL989362 | 0.82 | PIK3CA (0.84) | PIK3CAPIK3CB | |
| SCHEMBL12555276 | 0.81 | PIK3CA (0.66) | PIK3CAPIK3CB | |
| SCHEMBL12555280 | 0.81 | PIK3CA (0.81) | PIK3CAPIK3CB | |
| SCHEMBL991694 | 0.80 | PIK3CA (0.87) | PIK3CAPIK3CB | |
| SCHEMBL989704 | 0.80 | PIK3CA (1.00) | PIK3CAPIK3CB | |
| SCHEMBL989936 | 0.79 | PIK3CA (0.83) | PIK3CAPIK3CB | |
| SCHEMBL12555424 | 0.79 | PIK3CA (0.83) | PIK3CAPIK3CB | |
| SCHEMBL991344 | 0.79 | PIK3CA (0.81) | PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123971-A1 | BENZOPYRAN AND BENZOXEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2009-10-08 | — | — | WO | disclosed |