Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 20/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12535949 | 0.90 | PIK3CA (0.59) | PIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL1042550 | 0.88 | PIK3CA (0.56) | PIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL1041179 | 0.80 | PIK3CA (0.54) | PIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL15663278 | 0.77 | PIK3CA (0.47) | PIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL16233202 | 0.77 | PIK3CA (0.75) | PIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL1620046 | 0.76 | PIK3CA (0.67) | PIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL1620270 | 0.76 | PIK3CA (0.69) | PIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL1042467 | 0.76 | PIK3CA (0.59) | PIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL1040771 | 0.75 | PIK3CA (0.57) | PIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL1042918 | 0.75 | PIK3CA (0.75) | PIK3CAPIK3CBPIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123971-A1 | BENZOPYRAN AND BENZOXEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2009-10-08 | — | — | WO | disclosed |