Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 20/20 | 0.76 |
| ▸ | PIK3CB | P42338 | 10/20 | 0.76 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.76 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043553 | 0.88 | PIK3CA (0.73) | PIK3CAPIK3CBPIK3CGPIK3CD | |
| SCHEMBL1043275 | 0.87 | PIK3CA (1.00) | PIK3CAPIK3CBPIK3CGPIK3CD | |
| SCHEMBL1041525 | 0.85 | PIK3CA (0.70) | PIK3CAPIK3CBPIK3CGPIK3CD | |
| SCHEMBL1484515 | 0.85 | PIK3CA (0.69) | PIK3CAPIK3CBPIK3CGPIK3CD | |
| SCHEMBL1041471 | 0.82 | PIK3CA (0.65) | PIK3CAPIK3CBPIK3CGPIK3CD | |
| SCHEMBL1041707 | 0.82 | PIK3CA (0.69) | PIK3CAPIK3CBPIK3CGPIK3CD | |
| SCHEMBL1042816 | 0.81 | PIK3CA (0.64) | PIK3CAPIK3CBPIK3CGPIK3CD | |
| SCHEMBL1041991 | 0.81 | PIK3CA (0.86) | PIK3CAPIK3CBPIK3CGPIK3CD | |
| SCHEMBL12316606 | 0.80 | PIK3CA (0.64) | PIK3CAPIK3CBPIK3CGPIK3CD | |
| SCHEMBL16105442 | 0.80 | PIK3CA (0.62) | PIK3CAPIK3CBPIK3CGPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123971-A1 | BENZOPYRAN AND BENZOXEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2009-10-08 | — | — | WO | disclosed |