Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 4/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12819956 | 0.80 | SMN1; SMN2 (0.50) | GSK3BPTPN1RAB9A | |
| SCHEMBL3341123 | 0.78 | TPMT (0.54) | TPMTCA1CA2GSK3BPDPK1 | |
| SCHEMBL11695106 | 0.78 | GSK3B (0.64) | TPMTCA1CA2GSK3BPDPK1 | |
| SCHEMBL12153522 | 0.78 | NPC1 (0.60) | CA1CA2PTPN1NPC1RAB9A | |
| SCHEMBL12300577 | 0.78 | GSK3B (0.38) | GSK3BPTPN1NPC1RAB9A | |
| SCHEMBL661834 | 0.76 | SMN1; SMN2 (0.57) | TPMTCA1CA2GSK3BPDPK1 | |
| SCHEMBL743683 | 0.76 | TPMT (0.52) | TPMTCA1CA2GSK3BPDPK1 | |
| SCHEMBL5068712 | 0.76 | HDAC3 (0.55) | TPMTCA1CA2GSK3BPDPK1 | |
| SCHEMBL13191468 | 0.76 | MAPT (0.45) | NPC1RAB9A | |
| SCHEMBL8751033 | 0.76 | GSK3B (0.64) | CA1CA2GSK3BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |