Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 19/20 | 0.45 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14016552 | 0.93 | CALCRL (0.49) | CALCRLRAMP1 | |
| SCHEMBL14016560 | 0.92 | CALCRL (0.50) | CALCRLRAMP1 | |
| SCHEMBL13655640 | 0.92 | CALCRL (0.48) | CALCRLRAMP1 | |
| SCHEMBL14016505 | 0.89 | CALCRL (0.48) | CALCRLRAMP1 | |
| SCHEMBL13655710 | 0.89 | CALCRL (0.47) | CALCRLRAMP1 | |
| SCHEMBL13655820 | 0.88 | CALCRL (0.46) | CALCRLRAMP1 | |
| SCHEMBL14016467 | 0.86 | CALCRL (0.47) | CALCRLRAMP1 | |
| SCHEMBL14017817 | 0.85 | CALCRL (0.55) | CALCRLRAMP1 | |
| SCHEMBL13655693 | 0.85 | CALCRL (0.46) | CALCRLRAMP1CHRM4CHRM1 | |
| SCHEMBL14044251 | 0.85 | CALCRL (0.51) | CALCRLRAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108648-A1 | Selected CGRP antagonists, method for their manufacture and use as medicines | Boehringer Ingelheim International GmbH (DE) | 2009-10-14 | — | — | EP | disclosed |