Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.62 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14016449 | 0.92 | CALCRL (0.67) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14017777 | 0.91 | CALCRL (0.66) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14017004 | 0.91 | CALCRL (0.66) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14017775 | 0.91 | CALCRL (0.64) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14036380 | 0.91 | CALCRL (0.60) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14036292 | 0.91 | CALCRL (0.66) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14036195 | 0.90 | CALCRL (0.77) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14036164 | 0.90 | CALCRL (0.65) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14036200 | 0.90 | CALCRL (0.59) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14036225 | 0.90 | CALCRL (0.65) | CALCRLRAMP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108648-A1 | Selected CGRP antagonists, method for their manufacture and use as medicines | Boehringer Ingelheim International GmbH (DE) | 2009-10-14 | — | — | EP | disclosed |