Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 6/20 | 0.79 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.75 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | PDE4A | P27815 | 1/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.70 |
| ▸ | TTPA | P49638 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627940 | 1.00 | PSEN1 (0.79) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL627141 | 0.99 | PSEN1 (0.78) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL627127 | 0.99 | PSEN1 (0.78) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL23766590 | 0.99 | PSEN1 (0.78) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL633986 | 0.99 | PSEN1 (0.78) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL31330188 | 0.97 | PSEN1 (0.81) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL627980 | 0.97 | PSEN1 (0.81) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL2141324 | 0.97 | PSEN1 (0.81) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL634036 | 0.94 | PSEN1 (0.82) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL2142325 | 0.94 | PSEN1 (0.82) | PSEN1GSTO1PTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608638-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2009-10-27 | — | — | US | disclosed |
| US-7608638-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2009-10-27 | — | — | US | disclosed |