Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13178479 | 0.96 | HRH3 (0.56) | HRH3CYP2C19SCN5ACYP1A2CARM1 | |
| SCHEMBL13661321 | 0.94 | HRH3 (0.48) | HRH3CYP2C19SCN5ACYP1A2CARM1 | |
| SCHEMBL7326006 | 0.94 | HRH3 (0.60) | HRH3CYP2C19SCN5ACYP1A2CARM1 | |
| SCHEMBL13766333 | 0.94 | HRH3 (0.52) | HRH3CYP2C19SCN5ACYP1A2CARM1 | |
| SCHEMBL21727231 | 0.90 | HRH3 (0.52) | HRH3CYP2C19SCN5ACYP1A2CARM1 | |
| SCHEMBL9120834 | 0.90 | HRH3 (0.52) | HRH3CYP2C19SCN5ACYP1A2CARM1 | |
| SCHEMBL12612802 | 0.90 | CYP2C19 (0.52) | HRH3CYP2C19CYP1A2MEN1GLA | |
| SCHEMBL6733235 | 0.88 | CARM1 (0.48) | HRH3CYP2C19SCN5ACYP1A2CARM1 | |
| SCHEMBL16675490 | 0.87 | HRH3 (0.47) | HRH3CYP2C19SCN5ACYP1A2CARM1 | |
| SCHEMBL14479170 | 0.84 | CYP2C19 (0.46) | CYP2C19CYP1A2MEN1GLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |