Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17946346 | 0.91 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL17128133 | 0.86 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL18912571 | 0.80 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL15340724 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL19001214 | 0.78 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL14529024 | 0.77 | SMN1; SMN2 (0.68) | SMN1; SMN2KMT2ANPC1RAB9ACYP2C19 | |
| SCHEMBL26077286 | 0.77 | MEN1 (0.62) | SMN1; SMN2KMT2ANPC1RAB9ACYP2C19 | |
| SCHEMBL13431982 | 0.76 | SMN1; SMN2 (0.64) | SMN1; SMN2KMT2ANPC1RAB9ACYP2C19 | |
| SCHEMBL4281745 | 0.76 | MEN1 (0.73) | SMN1; SMN2KMT2ANPC1RAB9ACYP2C19 | |
| SCHEMBL13661301 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2KMT2ANPC1RAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |