Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | ACR | P10323 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11986102 | 0.98 | POLB (0.52) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL12242713 | 0.98 | POLB (0.52) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL12733727 | 0.96 | ELANE (0.52) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL12242656 | 0.94 | TDP1 (0.49) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL19757164 | 0.94 | POLB (0.49) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL12242788 | 0.94 | TDP1 (0.49) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL12242616 | 0.94 | TDP1 (0.49) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL19757162 | 0.94 | POLB (0.49) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL12172627 | 0.93 | MAPT (0.49) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL13289773 | 0.93 | POLB (0.48) | POLBAPEX1HTTTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7597945-B2 | Optical compensation film; mixture of three (meth)acrylate monomers: e.g. 2,7-bis(acryloyloxyhexyloxy-1,4-phenylenecarbonyloxy)fluorene, a bis 2-fluoroacrylate monomer, and a cyanobiphenyloxyalkanol ester of (meth)acrylic acid; hardness, heat resistance, weatherability, colorless, LC physical properties | CHISSO CORPORATION (JP) | 2009-10-06 | — | — | US | disclosed |