Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13667834 | 0.80 | CYP2A6 (0.60) | CYP2A6ALDH1A1CHRNA7SMN1; SMN2CRHBP | |
| SCHEMBL3106949 | 0.74 | CYP2A6 (0.70) | CYP2A6ALDH1A1CHRNA7SMN1; SMN2CRHBP | |
| SCHEMBL13913436 | 0.73 | CYP2A6 (0.51) | CYP2A6ALDH1A1CHRNA7SMN1; SMN2CRHBP | |
| SCHEMBL2141390 | 0.72 | MIF (0.62) | CYP2A6ALDH1A1TRPA1CYP3A4MIF | |
| SCHEMBL29616337 | 0.72 | MIF (0.62) | CYP2A6ALDH1A1TRPA1CYP3A4MIF | |
| SCHEMBL19563724 | 0.72 | CYP2A6 (0.55) | CYP2A6ALDH1A1CHRNA7SMN1; SMN2CRHBP | |
| SCHEMBL2248829 | 0.71 | CYP2A6 (1.00) | CYP2A6ALDH1A1CHRNA7SMN1; SMN2CRHBP | |
| SCHEMBL18666075 | 0.70 | CYP2A6 (0.67) | CYP2A6ALDH1A1CHRNA7SMN1; SMN2CRHBP | |
| SCHEMBL7987474 | 0.70 | CYP2A6 (0.67) | CYP2A6ALDH1A1CHRNA7SMN1; SMN2CRHBP | |
| SCHEMBL2792315 | 0.70 | CYP2A6 (0.67) | CYP2A6ALDH1A1CHRNA7SMN1; SMN2CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270372-A1 | NOVEL DERIVATIVES OF BENZIMIDAZOLE AND IMIDAZO-PYRIDINE AND THEIR USE AS MEDICAMENTS | SOCIETE DE CONSEILS DE RECHERCHES ET (FR) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270372-A1 | NOVEL DERIVATIVES OF BENZIMIDAZOLE AND IMIDAZO-PYRIDINE AND THEIR USE AS MEDICAMENTS | MC4R, MC3R, MC1R | CYP2A6 1814/4885ALDH1A1 2349/4885TRPA1 601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.