⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13076412 | 0.84 | TDP1 (0.32) | — | |
| SCHEMBL20808577 | 0.79 | — | — | |
| SCHEMBL24625541 | 0.79 | — | — | |
| SCHEMBL16378625 | 0.79 | — | — | |
| SCHEMBL21263777 | 0.76 | — | — | |
| SCHEMBL18378601 | 0.73 | — | — | |
| SCHEMBL18757731 | 0.73 | — | — | |
| SCHEMBL14153090 | 0.73 | — | — | |
| SCHEMBL20934679 | 0.71 | — | — | |
| SCHEMBL18773490 | 0.71 | TDP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530314-B2 | Method for manufacturing both organic-inorganic composite synthetic resin containing highly flame-retardant organically modified nanoparticle and processed product thereof | KYUNG DONG ONE CORPORATION (KR) | 2022-12-20 | — | — | US | disclosed |
| WO-2016112120-A1 | COMPOUNDS FOR TREATMENT OF CYSTIC FIBROSIS | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2016-07-14 | — | — | WO | disclosed |
| WO-2015076801-A1 | SUBSTITUTED TRIAZINE BMI-1 INHIBITORS | PTC THERAPEUTICS, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
| WO-2013032591-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INFINITY PHARMACEUTICALS INC. (US) | 2013-03-07 | — | — | WO | disclosed |
| WO-2009126841-A1 | ENZYMATIC BIOSENSORS WITH ENHANCED ACTIVITY RETENTION FOR DETECTION OF ORGANIC COMPOUNDS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2009-10-15 | — | — | WO | disclosed |