Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.70 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664674 | 0.83 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3BCL2A1 | |
| SCHEMBL13665280 | 0.81 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3BCL2A1 | |
| SCHEMBL13664778 | 0.80 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3BCL2A1 | |
| SCHEMBL13664720 | 0.80 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3BCL2A1ADRB1 | |
| SCHEMBL13664680 | 0.80 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3BCL2A1 | |
| SCHEMBL13664892 | 0.78 | SLC6A2 (0.82) | SLC6A2SLC6A4SLC6A3BCL2A1 | |
| SCHEMBL13665273 | 0.76 | SLC6A2 (0.78) | SLC6A2SLC6A4SLC6A3BCL2A1 | |
| SCHEMBL13664780 | 0.75 | SLC6A2 (0.77) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11870004 | 0.72 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13664863 | 0.70 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |