Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11402078 | 0.83 | EPHX1 (0.63) | SMN1; SMN2EPHX1EPHX2GAACYP3A4 | |
| SCHEMBL11305719 | 0.83 | EPHX1 (0.63) | SMN1; SMN2EPHX1EPHX2GAACYP3A4 | |
| SCHEMBL13665307 | 0.83 | EPHX1 (0.54) | SMN1; SMN2EPHX1EPHX2GAACYP3A4 | |
| SCHEMBL11875959 | 0.81 | EPHX1 (0.61) | SMN1; SMN2EPHX1EPHX2GAACYP3A4 | |
| SCHEMBL8972648 | 0.81 | NPC1 (0.53) | SMN1; SMN2GAAALDH1A1CA2CA9 | |
| SCHEMBL13664732 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2EPHX1EPHX2CYP3A4 | |
| SCHEMBL11557567 | 0.80 | EPHX1 (0.59) | SMN1; SMN2EPHX1EPHX2GAACYP3A4 | |
| SCHEMBL16160133 | 0.79 | EPHX1 (0.54) | SMN1; SMN2EPHX1EPHX2GAACYP3A4 | |
| SCHEMBL20971627 | 0.79 | HPGD (0.57) | SMN1; SMN2ALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL19208177 | 0.79 | HPGD (0.57) | SMN1; SMN2ALDH1A1NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |