Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664810 | 0.88 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL13664873 | 0.86 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL13664695 | 0.85 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL13664817 | 0.83 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL13664685 | 0.83 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL13664902 | 0.82 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL13664904 | 0.80 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL13664818 | 0.71 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL13664780 | 0.71 | SLC6A2 (0.77) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL13664895 | 0.70 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |