SCHEMBL13664833

SCHEMBL13664833

NC(CO)(CCc1ccc(OCCCCCCF)c(C(F)(F)F)c1)COP(=O)(O)O

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 20/20 0.67
S1PR3 Q99500 14/20 0.67
S1PR4 O95977 3/20 0.53
S1PR5 Q9H228 3/20 0.53
S1PR2 O95136 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13665143 1.00 S1PR1 (0.67) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL13665563 1.00 S1PR1 (0.67) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL13851946 0.91 S1PR1 (0.78) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL29735087 0.91 S1PR1 (0.78) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL13851934 0.91 S1PR1 (0.78) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL13851931 0.91 S1PR1 (0.78) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL13463831 0.91 S1PR1 (0.78) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL13851944 0.91 S1PR1 (0.78) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL13851933 0.91 S1PR1 (0.78) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL86567 0.90 S1PR1 (0.61) S1PR1S1PR3S1PR4S1PR5S1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009119858-A1 BENZENE COMPOUND, AND USE THEREOF FOR MEDICAL PURPOSES 田辺三菱製薬株式会社 (JP) 2009-10-01 WO disclosed