Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 9/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664973 | 0.93 | F10 (0.42) | SMN1; SMN2F10HSD17B10KDM4EALDH1A1 | |
| SCHEMBL13665087 | 0.92 | NPC1 (0.42) | SMN1; SMN2HSD17B10KDM4EALDH1A1MEN1 | |
| SCHEMBL4325368 | 0.92 | SMN1; SMN2 (0.46) | SMN1; SMN2F10HSD17B10KDM4EALDH1A1 | |
| SCHEMBL13665053 | 0.92 | SMN1; SMN2 (0.40) | SMN1; SMN2F10HSD17B10KDM4EALDH1A1 | |
| SCHEMBL13665052 | 0.91 | HSD17B10 (0.40) | SMN1; SMN2F10HSD17B10KDM4EALDH1A1 | |
| SCHEMBL13664979 | 0.90 | F10 (0.40) | SMN1; SMN2F10HSD17B10 | |
| SCHEMBL4331028 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2F10HSD17B10KDM4EALDH1A1 | |
| SCHEMBL4331029 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2F10HSD17B10KDM4EALDH1A1 | |
| SCHEMBL13664984 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2F10HSD17B10KDM4EALDH1A1 | |
| SCHEMBL13665054 | 0.88 | F10 (0.40) | SMN1; SMN2F10HSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |