Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4319944 | 0.94 | F10 (0.44) | F10SMN1; SMN2KCNH2KDM4EALDH1A1 | |
| SCHEMBL13664979 | 0.91 | F10 (0.40) | F10SMN1; SMN2KCNH2 | |
| SCHEMBL13664966 | 0.91 | F10 (0.43) | F10SMN1; SMN2KCNH2KDM4EALDH1A1 | |
| SCHEMBL13664976 | 0.91 | GRM5 (0.46) | F10SMN1; SMN2KCNH2KDM4EALDH1A1 | |
| SCHEMBL13664978 | 0.90 | F10 (0.39) | F10SMN1; SMN2KCNH2KDM4EALDH1A1 | |
| SCHEMBL13664960 | 0.90 | F10 (0.43) | F10SMN1; SMN2KCNH2KDM4EALDH1A1 | |
| SCHEMBL13665074 | 0.90 | F10 (0.47) | F10SMN1; SMN2KCNH2 | |
| SCHEMBL4325368 | 0.90 | SMN1; SMN2 (0.46) | F10SMN1; SMN2KCNH2KDM4EALDH1A1 | |
| SCHEMBL13744683 | 0.89 | F10 (0.43) | F10SMN1; SMN2KCNH2KDM4EALDH1A1 | |
| SCHEMBL13744838 | 0.89 | SMN1; SMN2 (0.45) | F10SMN1; SMN2KCNH2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |