Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.43 |
| ▸ | F10 | P00742 | 7/20 | 0.43 |
| ▸ | GRM5 | P41594 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 3/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664976 | 0.96 | GRM5 (0.46) | F10GRM5SMN1; SMN2 | |
| SCHEMBL13664966 | 0.90 | F10 (0.43) | F10GRM5SMN1; SMN2 | |
| SCHEMBL4318062 | 0.90 | F10 (0.45) | ABL1F10GRM5MAPK1SMN1; SMN2 | |
| SCHEMBL4318072 | 0.90 | F10 (0.45) | ABL1F10GRM5MAPK1SMN1; SMN2 | |
| SCHEMBL4319944 | 0.89 | F10 (0.44) | ABL1F10MAPK1SMN1; SMN2 | |
| SCHEMBL13664971 | 0.88 | F10 (0.42) | F10GRM5SMN1; SMN2 | |
| SCHEMBL2944358 | 0.88 | NPY5R (0.46) | ABL1F10MAPK1SMN1; SMN2JAK1 | |
| SCHEMBL2944357 | 0.88 | NPY5R (0.46) | ABL1F10MAPK1SMN1; SMN2JAK1 | |
| SCHEMBL13664960 | 0.88 | F10 (0.43) | F10MAPK1SMN1; SMN2 | |
| SCHEMBL13664987 | 0.88 | JAK1 (0.42) | ABL1F10SMN1; SMN2RIN1JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |