Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664995 | 0.94 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2AMEN1HSD17B10MAPT | |
| SCHEMBL13665005 | 0.92 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2AMEN1HSD17B10MAPT | |
| SCHEMBL13665001 | 0.92 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2AMEN1HSD17B10MAPT | |
| SCHEMBL2949585 | 0.90 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2AMEN1HSD17B10MAPT | |
| SCHEMBL2949583 | 0.90 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2AMEN1HSD17B10MAPT | |
| SCHEMBL4327128 | 0.90 | SMN1; SMN2 (0.59) | SMN1; SMN2KMT2AMEN1HSD17B10MAPT | |
| SCHEMBL4327123 | 0.90 | SMN1; SMN2 (0.59) | SMN1; SMN2KMT2AMEN1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL2942898 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AMEN1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL2942900 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AMEN1HSD17B10MAPT | |
| SCHEMBL13290940 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AMEN1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |