Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4325430 | 0.87 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EALDH1A1LMNANPC1 | |
| SCHEMBL4327565 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4EALDH1A1GAALMNA | |
| SCHEMBL4325248 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EALDH1A1GAALMNA | |
| SCHEMBL13664964 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4EALDH1A1GAALMNA | |
| SCHEMBL4326027 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EALDH1A1GAALMNA | |
| SCHEMBL13665038 | 0.82 | SMN1; SMN2 (0.63) | SMN1; SMN2KDM4EALDH1A1LMNANPC1 | |
| SCHEMBL13665022 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4EALDH1A1GAALMNA | |
| SCHEMBL13665012 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EALDH1A1GAALMNA | |
| SCHEMBL13665013 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EALDH1A1GAALMNA | |
| SCHEMBL4327316 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |