Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13665066 | 0.94 | NPC1 (0.44) | NPC1RAB9AKMT2ACASP3SENP7 | |
| SCHEMBL13664967 | 0.91 | SMN1; SMN2 (0.44) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL13665067 | 0.90 | NPC1 (0.41) | NPC1RAB9AKMT2ACASP3SENP7 | |
| SCHEMBL13665070 | 0.90 | NPC1 (0.41) | NPC1RAB9AKMT2ACASP3SENP7 | |
| SCHEMBL13665068 | 0.88 | JAK1 (0.42) | NPC1RAB9AKMT2ACASP3SENP7 | |
| SCHEMBL13665069 | 0.88 | NPC1 (0.43) | NPC1RAB9AKMT2ACASP3SENP7 | |
| SCHEMBL13665080 | 0.88 | NPC1 (0.46) | NPC1RAB9AKMT2ACASP3SENP7 | |
| SCHEMBL13665073 | 0.87 | NPC1 (0.42) | NPC1RAB9AKMT2ACASP3SENP7 | |
| SCHEMBL13665071 | 0.87 | NPC1 (0.41) | NPC1RAB9AKMT2ACASP3SENP7 | |
| SCHEMBL13665072 | 0.87 | NPC1 (0.42) | NPC1RAB9AKMT2ACASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |