Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13665085 | 0.94 | ABL1 (0.46) | NPC1RAB9AKMT2ACASP3SENP7 | |
| SCHEMBL13664971 | 0.92 | F10 (0.42) | GRM5 | |
| SCHEMBL13665080 | 0.89 | NPC1 (0.46) | NPC1RAB9AKMT2ACASP3SENP7 | |
| SCHEMBL13665082 | 0.89 | NPC1 (0.46) | NPC1RAB9AKMT2ACASP3SENP7 | |
| SCHEMBL13665078 | 0.88 | NPC1 (0.49) | NPC1RAB9AKMT2ACASP3SENP7 | |
| SCHEMBL13665067 | 0.87 | NPC1 (0.41) | NPC1RAB9AKMT2ACASP3SENP7 | |
| SCHEMBL4318062 | 0.86 | F10 (0.45) | ABL1GRM5 | |
| SCHEMBL4318072 | 0.86 | F10 (0.45) | ABL1GRM5 | |
| SCHEMBL13665087 | 0.84 | NPC1 (0.42) | NPC1RAB9AKMT2ACASP3SENP7 | |
| SCHEMBL13665094 | 0.84 | KMT2A (0.42) | NPC1RAB9AKMT2ACASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |