Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR10 | P46092 | 15/20 | 0.63 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13665564 | 0.90 | CCR10 (0.67) | CCR10F2 | |
| SCHEMBL13665579 | 0.90 | CCR10 (0.62) | CCR10F2 | |
| SCHEMBL13665195 | 0.89 | CCR10 (0.78) | CCR10F2 | |
| SCHEMBL1035513 | 0.88 | CCR10 (0.81) | CCR10 | |
| SCHEMBL13665908 | 0.88 | CCR10 (0.69) | CCR10F2 | |
| SCHEMBL13665634 | 0.88 | CCR10 (0.64) | CCR10F2 | |
| SCHEMBL13665556 | 0.88 | CCR10 (0.78) | CCR10 | |
| SCHEMBL13665649 | 0.88 | CCR10 (0.66) | CCR10 | |
| SCHEMBL13665903 | 0.87 | CCR10 (0.68) | CCR10F2 | |
| SCHEMBL13665171 | 0.87 | CCR10 (0.68) | CCR10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009126675-A1 | 2-SULFONYLAMINO-4-HETEROARYL BUTYRAMIDE ANTAGONISTS OF CCR10 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-15 | — | — | WO | disclosed |