Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.58 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.58 |
| ▸ | ITGAL | P20701 | 20/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13662074 | 0.87 | ITGB2 (0.64) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL13662072 | 0.79 | ITGB2 (0.64) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL18868509 | 0.79 | ITGB2 (0.59) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL22296915 | 0.79 | ITGB2 (0.70) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL18867979 | 0.79 | ITGB2 (0.70) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL12507169 | 0.78 | ITGB2 (0.74) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL13665399 | 0.78 | ITGB2 (0.64) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL13667993 | 0.78 | ITGB2 (0.84) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL19157816 | 0.78 | ITGB2 (0.67) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL18867976 | 0.78 | ITGB2 (0.67) | ITGB2ICAM1ITGALCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009128932-A1 | DELIVERY OF LFA-1 ANTAGONISTS TO THE GASTROINTESTINAL SYSTEM | SARCODE CORPORATION (US) | 2009-10-22 | — | — | WO | disclosed |