SCHEMBL136654

SCHEMBL136654

Cc1cnc2c(ccc3c(C)c(C)cnc32)c1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 1.00
CCR8 P51685 5/20 1.00
CCR5 P51681 4/20 1.00
L3MBTL1 Q9Y468 3/20 0.46
NPC1 O15118 1/20 0.46
HSP90AA1 P07900 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
AXL P30530 1/20 0.32
PRKCI P41743 1/20 0.32
NOS3 P29474 2/20 0.32
NOS2 P35228 2/20 0.32
NOS1 P29475 1/20 0.32
CYP1A2 P05177 2/20 0.31
CYP2A6 P11509 2/20 0.31
TSHR P16473 1/20 0.31
PLAU P00749 1/20 0.31
OPRK1 P41145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28297883 1.00 CCR1 (1.00) CCR1CCR8CCR5L3MBTL1NPC1
Water SCHEMBL28424933 0.97 CCR1 (0.95) CCR1CCR8CCR5L3MBTL1NPC1
SCHEMBL30753486 0.97 CCR1 (0.95) CCR1CCR8CCR5L3MBTL1NPC1
SCHEMBL11731095 0.97 CCR1 (0.95) CCR1CCR8CCR5L3MBTL1NPC1
SCHEMBL28229864 0.97 CCR1 (0.95) CCR1CCR8CCR5L3MBTL1NPC1
SCHEMBL29569064 0.97 CCR1 (0.95) CCR1CCR8CCR5L3MBTL1NPC1
SCHEMBL29354722 0.97 CCR1 (0.95) CCR1CCR8CCR5L3MBTL1NPC1
Water SCHEMBL7574656 0.93 CCR1 (0.86) CCR1CCR8CCR5L3MBTL1NPC1
SCHEMBL28430950 0.93 CCR1 (0.86) CCR1CCR8CCR5L3MBTL1NPC1
Hydrochloric Acid SCHEMBL4591597 0.89 CCR1 (0.79) CCR1CCR8CCR5L3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2319 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120158296-A Application of hybrid halide in enhancing nonlinear optical effect in high-pressure environment 电子科技大学 2025-06-17 CN claimed
CN-115850177-B Dibenzo [ c, e ] azepine and its derivative and nickel catalytic synthesis method 湖南大学 2025-06-10 CN claimed
CN-119874591-A Preparation method of 2-pyrrolidone derivative 浙江理工大学 2025-04-25 CN claimed
CN-119751437-A Synthesis method of Se-deuterated methyl-thioridazine compound 浙江工业大学 2025-04-04 CN claimed
CN-119708623-A Heat stabilizer and preparation method thereof 西尼尔(山东)新材料科技有限公司 2025-03-28 CN claimed
CN-116272969-B Catalyst for synthesizing hexamethylenediamine and preparation method thereof 中国科学院长春应用化学研究所 2025-03-07 CN claimed
CN-119569558-A Method for synthesizing 2-phenylpropionic acid by nickel-catalyzed reaction of styrene and carbon dioxide 中国石油化工股份有限公司 2025-03-07 CN claimed
WO-2025043152-A1 METHODS OF DEALKENYLATIVE AMINATION AND AZIDATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-27 WO claimed
CN-115716847-B Preparation method of B, si-bimetallic reagent 苏州大学 2025-02-25 CN claimed
CN-119306772-A Method for synthesizing metallocene borate 中国科学院大连化学物理研究所 2025-01-14 CN claimed
EP-0369864-A2 Process for producing aromatic amines SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-05-23 EP claimed
EP-0326835-A1 Porphyric insecticides The Board of Trustees for the University of Illinois (US) 1989-08-09 EP claimed
EP-0091383-B1 PROCESS FOR THE CATALYTIC REDUCTION OF NITRO-AROMATIC COMPOUNDS Montedison S.p.A. (IT) 1987-03-04 EP claimed
EP-0097592-B1 PROCESS FOR CATALYTICALLY REDUCING NITROAROMATIC COMPOUNDS Montedison S.p.A. (IT) 1986-12-10 EP claimed
EP-0169650-A2 Process for preparing aromatic urethanes from nitroaromatic compounds Montedison S.p.A. (IT) 1986-01-29 EP claimed
US-4535162-A USING GROUP 8 METAL COORDINATION CATALYSTS MONTEDISON S.P.A. (IT) 1985-08-13 US claimed
EP-0097592-A2 Process for catalytically reducing nitroaromatic compounds Montedison S.p.A. (IT) 1984-01-04 EP claimed
US-4414417-A Process for the catalytic reduction of unsaturated ketones MONTEDISON, S.P.A. (IT) 1983-11-08 US claimed
EP-0091383-A1 Process for the catalytic reduction of nitro-aromatic compounds Montedison S.p.A. (IT) 1983-10-12 EP claimed
US-4290961-A Process for catalytically reducing carbonyl compounds MONTEDISON S.P.A. (IT) 1981-09-22 US claimed