Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR10 | P46092 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13665160 | 0.94 | CCR10 (0.44) | CCR10ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL1076161 | 0.91 | CCR10 (0.51) | CCR10ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL13665881 | 0.88 | CCR10 (0.52) | CCR10ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL13665267 | 0.87 | CCR10 (0.58) | CCR10 | |
| SCHEMBL1311486 | 0.86 | CCR10 (0.55) | CCR10ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL13665637 | 0.84 | CCR10 (0.60) | CCR10 | |
| SCHEMBL13665867 | 0.82 | CCR10 (0.40) | CCR10ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL13665625 | 0.82 | CCR10 (0.46) | CCR10 | |
| SCHEMBL13665893 | 0.82 | CCR10 (0.46) | CCR10 | |
| SCHEMBL1074637 | 0.81 | CCR10 (0.58) | CCR10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009126675-A1 | 2-SULFONYLAMINO-4-HETEROARYL BUTYRAMIDE ANTAGONISTS OF CCR10 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-15 | — | — | WO | disclosed |