Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 5/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13665684 | 0.89 | GCK (0.34) | GCKKCNH2 | |
| SCHEMBL1076316 | 0.84 | GCK (0.37) | GCKALOX5APFEN1KCNH2 | |
| SCHEMBL13665435 | 0.84 | GCK (0.33) | GCK | |
| SCHEMBL1076395 | 0.83 | GCK (0.35) | GCKALOX5APFEN1KCNH2 | |
| SCHEMBL1075263 | 0.83 | GCK (0.38) | GCKKCNH2 | |
| SCHEMBL1076441 | 0.82 | GCK (0.39) | GCKKCNH2 | |
| SCHEMBL4440677 | 0.78 | GCK (0.33) | GCK | |
| SCHEMBL13665666 | 0.76 | GCK (0.43) | GCKKCNH2 | |
| SCHEMBL13665416 | 0.75 | GCK (0.39) | GCK | |
| SCHEMBL4447141 | 0.74 | GCK (0.33) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009125873-A1 | FUSED RING COMPOUNDS AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-15 | — | — | WO | disclosed |