Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.61 |
| ▸ | ITGAL | P20701 | 20/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL879396 | 0.88 | ITGB2 (0.77) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL18867834 | 0.88 | ITGB2 (0.77) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL22693777 | 0.87 | ITGB2 (0.79) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL22476509 | 0.87 | ITGB2 (0.79) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL18881150 | 0.82 | ITGB2 (0.67) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL13662248 | 0.79 | ITGB2 (0.63) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL16351763 | 0.78 | ITGB2 (0.59) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL20833712 | 0.78 | ITGB2 (0.75) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL20833868 | 0.78 | ITGB2 (0.75) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL13658250 | 0.77 | ITGB2 (0.77) | ITGB2ICAM1ITGALCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009128934-A1 | TOPICAL LFA-1 ANTAGONISTS FOR USE IN LOCALIZED TREATMENT OF IMMUNE RELATED DISORDERS | SARCODE CORPORATION (US) | 2009-10-22 | — | — | WO | disclosed |