Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13667367 | 1.00 | AVPR2 (0.42) | AVPR2AVPR1ALPAR1OPRM1OPRL1 | |
| SCHEMBL4312053 | 1.00 | AVPR2 (0.42) | AVPR2AVPR1ALPAR1OPRM1OPRL1 | |
| SCHEMBL4317565 | 0.88 | AVPR2 (0.42) | AVPR2AVPR1ALPAR1 | |
| SCHEMBL23138981 | 0.86 | AVPR2 (0.42) | AVPR2AVPR1ALPAR1CASP1 | |
| SCHEMBL4310582 | 0.85 | AVPR2 (0.34) | AVPR2AVPR1A | |
| Cenobamate SCHEMBL4308624 | 0.85 | POLB (0.46) | AVPR2AVPR1ALPAR1 | |
| Cenobamate SCHEMBL13667363 | 0.85 | POLB (0.46) | AVPR2AVPR1ALPAR1 | |
| Cenobamate SCHEMBL1682643 | 0.85 | POLB (0.46) | AVPR2AVPR1ALPAR1 | |
| Cenobamate SCHEMBL29410391 | 0.85 | POLB (0.46) | AVPR2AVPR1ALPAR1 | |
| SCHEMBL13667441 | 0.84 | CYP2C9 (0.41) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598279-B2 | Neurotherapeutic azole compounds | SK HOLDINGS CO., LTD. (KR) | 2009-10-06 | — | — | US | disclosed |
| US-7598279-B2 | Neurotherapeutic azole compounds | SK HOLDINGS CO., LTD. (KR) | 2009-10-06 | — | — | US | disclosed |