Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 10/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 2/20 | 0.31 |
| ▸ | IGF1R | P08069 | 2/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12068855 | 0.86 | TAAR1 (0.32) | HSPA5TAAR1 | |
| SCHEMBL19088037 | 0.80 | HSPA5 (0.36) | TNK2HSPA5RIPK1 | |
| SCHEMBL10082719 | 0.80 | HSPA5 (0.36) | TNK2HSPA5RIPK1 | |
| SCHEMBL12393393 | 0.80 | HSPA5 (0.36) | TNK2HSPA5RIPK1 | |
| SCHEMBL18666854 | 0.79 | TNK2 (0.35) | TNK2HSPA5TAAR1 | |
| SCHEMBL14052168 | 0.79 | TNK2 (0.35) | TNK2HSPA5TAAR1 | |
| SCHEMBL18667233 | 0.79 | TNK2 (0.35) | TNK2HSPA5TAAR1 | |
| SCHEMBL12294892 | 0.79 | TNK2 (0.35) | TNK2HSPA5TAAR1 | |
| SCHEMBL18666910 | 0.79 | TNK2 (0.35) | TNK2HSPA5TAAR1 | |
| SCHEMBL18636665 | 0.79 | TNK2 (0.35) | TNK2HSPA5TAAR1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132135-A1 | 1' -SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2009-10-29 | — | — | WO | disclosed |