Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12189911 | 0.93 | KMT2A (0.50) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL12112072 | 0.93 | TSHR (0.54) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25971375 | 0.91 | KMT2A (0.53) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25697432 | 0.91 | KMT2A (0.53) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17301944 | 0.91 | KMT2A (0.49) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25727242 | 0.91 | KMT2A (0.53) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL12543410 | 0.90 | MAPT (0.55) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL12543137 | 0.90 | MAPT (0.48) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL24673728 | 0.89 | KMT2A (0.51) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25830865 | 0.89 | KMT2A (0.51) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601796-B2 | polyamideether copolymer has a hydrophilic polyethylene glycol and a hydrophobic polyamino acid blocks; modified polyethylene glycol homopolymer; forming conjugate polymer drug; resin peptides; use in pharmaceutically acceptable compositions | INTEZYNE TECHNOLOGIES, INC. (US) | 2009-10-13 | — | — | US | disclosed |