Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.58 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.58 |
| ▸ | ITGAL | P20701 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13668205 | 0.85 | ITGB2 (0.41) | ITGB2ICAM1ITGAL | |
| SCHEMBL22296990 | 0.80 | ITGB2 (0.80) | ITGB2ICAM1ITGAL | |
| SCHEMBL13662177 | 0.79 | ITGB2 (0.81) | ITGB2ICAM1ITGAL | |
| SCHEMBL13662126 | 0.78 | ITGB2 (0.62) | ITGB2ICAM1ITGAL | |
| SCHEMBL13662081 | 0.76 | ITGB2 (0.65) | ITGB2ICAM1ITGAL | |
| SCHEMBL13662092 | 0.75 | ITGB2 (0.62) | ITGB2ICAM1ITGAL | |
| SCHEMBL13666672 | 0.73 | ITGB2 (0.56) | ITGB2ICAM1ITGAL | |
| SCHEMBL19158522 | 0.73 | ITGAL (0.77) | ITGB2ICAM1ITGAL | |
| SCHEMBL13662080 | 0.71 | ITGB2 (0.79) | ITGB2ICAM1ITGAL | |
| SCHEMBL17991461 | 0.71 | ITGAL (0.76) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009128933-A1 | AEROSOLIZED LFA-1 ANTAGONISTS FOR USE IN LOCALIZED TREATMENT OF IMMUNE RELATED DISORDERS | SARCODE CORPORATION (US) | 2009-10-22 | — | — | WO | disclosed |